EXTRACTS OF KNOXIA ROXBURGHII (SPRENG.) M. A. RAU INDUCE APOPTOSIS IN HUMAN MCF-7 BREAST CANCER CELLS VIA MITOCHONDRIAL PATHWAYS

Extracts of Knoxia roxburghii (Spreng.) M. A. Rau Induce Apoptosis in Human MCF-7 Breast Cancer Cells via Mitochondrial Pathways

Knoxia roxburghii (Spreng.) M.A.Rau (KR) is a plant clinically used in traditional Chinese medicine (TCM) for the treatment of cancer.The study objectives were to examine the effects of KR extracts, petroleum ether (PET), ethyl acetate (EtoAc), butanol (n-BuOH), and H2O-soluble fractions (HSF) of the 75% EtOH extraction on A549 (non-small cell lung

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Buzz Kill: Function and Proteomic Composition of Venom from the Giant Assassin Fly Dolopus genitalis (Diptera: Asilidae)

Assassin flies (Diptera: Asilidae) inject Eye Palette paralysing venom into insect prey during hunting, but their venoms are poorly characterised in comparison to those produced by spiders, scorpions, or hymenopteran insects.Here we investigated the composition of the venom of the giant Australian assassin fly Dolopus genitalis using a combination

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Features of histological structure and differential diagnostics of the diffuse-type giant cell tumor and its malignant form.

Background.Tenosynovial giant cell tumor of diffuse type is one of the most widespread tumor of joints, causing destruction of the soft tissues and bone articular surfaces.Objective.The purpose of the study was to formulate Glucosamine/Chondroitin approaches to histological differential diagnostics between diffuse-type giant cell tumor and its mali

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Prognostic Value of Concomitant Bronchiectasis in Newly Diagnosed Diffuse Panbronchiolitis Patients on a Maintenance Therapy with Macrolides

Background.Factors determining the prognosis of diffuse panbronchiolitis (DPB) remain unclear at present.The objective of this study was to identify the prognostic value of concomitant bronchiectasis in the macrolide treatment efficacy and exacerbation steel-cockrings risk in DPB patients.Methods.Data of patients initially diagnosed with DPB at the

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Exploratory analysis of PM2.5 variation trend of Tehran, Iran, in various time series and its relation with cardiovascular mortality rate using R software

Among the numerous air pollutants, the strongest proof for adverse health effects has been reported for particulate matter (PM).The aim of this study was the exploration of short-term associations of air pollution with mortalities Fever due to cardiovascular diseases (CVD) in Tehran, Iran, based on hospital and census data from 2007 to 2013.This de

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